Genetic testing

A genetic test shows the efficiency and toxicity of a drug in relation to your genes! Through a personalized approach, you will always know, throughout your entire life, which drugs are compatible for you and considerably reduce years of treatment potentially wasted on recommendations that do not reap wanted results.

Efficiency of a genetic test

The doctor will aim to deliver a quick prescription for the medication for you!

In case you have other health problems like: coagulation issues, heart problems, pancreas or liver complications, etc., you will be prescribed medication that will not affect them!

Have you been going to therapy and taking meds for years with no real results? Genetic testing will accurately determine the most efficient treatment for you!

In case of other complications in your disorder, you may find out which treatment will help best with the whole range of mental health issues.

Results will show faster!

Genetic tests are up to the highest standard, they are of an internationally recognized quality, and are offered by the best specialists in the field.

Diagnostics and consultations, all from the same source, no need to take your results someplace else!

 Drug compatibility tests are available for any and all mental disorders!

Within the Hope Clinic, we treat both mild and severe mental disorders!

You will always know which drug to choose, both now and in the future!

No matter the severity of your disorder, you will benefit from the ideal treatment for you!

All these benefits and many others are possible through the collaboration of the HOPE Clinic with SYNLAB.

clinica hope sigla
sigla clinica hope
synlab logo

Optimization of the therapeutic process through genetic testing

The whole healthcare system and every patient benefit considerably, not only in regard to costs:

It lowers the rate of psychiatric consultations with the purpose of adjusting dosage or swapping to a different drug-based treatment.

It lowers the total cost of the treatment process by eliminating unsuccessful therapy sessions

It lowers the risk of drug interactions and adverse reactions

Encourages patients’ compliance to treatment

Ce presupune tratamentul CORECT al unei tulburări psihice

În cadrul Clinicii Hope aplicăm programe complete de tratament la cele mai înalte standarde, conform ghidurilor și recomandărilor internaționale.

Să luăm un exemplu concret!

Schizofrenia este tratată complet urmând toți pașii:

1. Psihiatrie (pentru diagnostic și tratament)

2. Test genetic

3. Psihoeducație

4. Psihoterapie individuală

5. Curs de abilități sociale

Tratament Complet Clinica Hope

*Toate acestea alcătuiesc programul de tratament special destinat persoanelor cu această tulburare denumit „Conexiuni!

În cadrul Clinicii Hope tratăm o gamă variată de tulburări psihice indiferent de severitatea lor!

De la Tulburarea de personalitate Borderline, Tulburarea Bipolară, Schizofrenia, Anxietate, Depresie, Insomnie, Autism, etc.,

Specialiștii noștri sunt alături de tine pentru a îți oferii tratamente personalizate, evaluate multidisciplinar și validate prin investigații clinice!

test genetic

What is genetic testing?

Globally, 1 out of 4 individuals will be affected by a mental or neurological disorder at any point in their lives. Currently, around 450 million people suffer from such conditions, mental disorders thus being one of the main causes of disease and incapacitation.

SYNLAB has developed a new pharmacogenetic test in the fields of psychopharmaceutics and antidepressants. This test helps determine the efficiency and toxicity of drugs in relation to genetic variations, which affects the enzymes responsible for metabolizing meds, transporters, or the meds’ targets.

Genetic testing – In pharmacogenetics, specific portions of DNA are analyzed to discover potential hereditary genetic variation. These are responsible for, among others, the activity of the enzymes that activate or deactivate meds, as well as the activity of their transporters to and from the tissues.

Every human being has their own unique genetic profile that reacts differently to treatment. Even if a specific treatment proves to be efficient in treating a wide group of patients, there will always be exceptions. Furthermore, even when there is a response to the treatment we are getting, that response can potentially cause adverse reactions, for some patients, the reactions could even lead to death.

Benefits of genetic testing

Taking individual response to medication is recommended to all medical professions and specializations. Utilizing pharmacogenetic analyses is especially valuable for the following categories of medication:

  • Analgesics/Anti-rheumatic drugs
  • Antibiotics/Antivirals
  • Antimycotics/Antidepressants
  • Psychotropics/Antidiabetics
  • Anti-hypertensives
  • Anticoagulants
  • Chemotherapy
  • Proton pump inhibitors
  • Statins
  • Urology

Genetic testing - How do you take genetic tests?

pasul 1 test


A box for bleeding

■■ Sampling and shipping instructions

■■ Test request and consent forms

pasul 2 test


■■ Organized by SYNLAB

pasul 3 test

MULTIPLEX Genetic testing

■■ Analyzes more than

32 key genes

■■ For more than 160 genetic variants affecting drug activation, transport and breakdown

pasul 4 test


■■ One-page summary with

key results

■■ Detailed report with full interpretation of the patient’s phenotype

Personal genetic profile

Genetic testing – Most people present genetic varieties that affect the protein involved in activating, transporting, and eliminating drugs. Up to 20% of patients in ambulatory treatment exhibit adverse reactions to meds, and 10-20% of inpatients have at least one RAM type med administered to them during their stay at the hospital.

Genetic testing provides tools for examining the individual genetic profile of the patient to personalize the choice and dosage of meds, in order to increase the probability of success of the treatment, and reduce the risk of negative effects or of administering an inefficient treatment.

For every gene and category of meds, patients are categorized in one of the following groups:
1. Slow metabolizer

The enzyme is inactive.

High drug concentration in the blood increases risk of side-effects.

The prodrug is not activated, and its administering is without therapeutic effect.

Alternative medication is required.

2. Intermediate metabolizer

Reduced enzyme activity

Medication dosage must be adjusted

Inhibiting medication shows risk of becoming a slow metabolizer

3. Normal metabolizer

Normal enzyme activity

Drug and prodrug dosage can be prescribed according to standard procedures.

4. Ultra-rapid metabolizers

Intense enzyme activity

If the drug is degraded by the enzymes, the actual concentration will be reduced, and the therapeutic process can be diminished.

Careful for prodrugs that are excessively activated and present the risk of overdose.

Our pharmacogenetic profile

Enzyme activity and transporters of an individual depends on the nature and number of genetic variants present.

Most common types of genetic variation appear thanks to single nucleoid variants (SNV), or polymorphisms (SNPs). They can function like biological markers, helping researchers localize the genes that have to do with the disease. On the other hand, if SNVs intervene in a gene or region responsible with adjustment that is close to a gene, they can play a more direct role in the disease, affecting the gene’s functioning or activity.

In this context, we analyze SNVs in the following:

profilul psihologic

Pharmacogenetically relevant genes

Gene Relevante Farmacogenetic

Sample result:

Tabel test genetic

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Synlab my PSY genetic test


PGx is highly relevant in adjusting neuropsychiatric drug treatment in over 80% of cases.


PGx contributes to treatment planning and implementation in a targeted manner.


PGx optimizes tolerability and reduces side effects of psychiatric treatment.


Up to 30% of all patients with depression experience no beneficial effects from treatment.

Genetic testing – Patients that follow a treatment according to PGx indications, experience less adverse reactions to meds, and the costs of medical healthcare, as well as doctor visits, are decreased in comparison to non-PGx-coordinated patients.

A genetic test provides important information about your genetic profile, analyzing genes responding to the multiple meds used in treating the following: Bipolar personality disorder, Borderline personality disorder, Schizophrenia, Anxiety, Depression, Insomnia, Autism, ADHD, Post-traumatic stress disorder, etc.

The chance to select the right meds for you is only a step away with genetic testing! We collect analyses right in our clinic, and the interpreted results will reach you, and our specialists, in order to make sure you are following the correct steps towards getting better.

Take a genetic test and leave your worries behind!